Can your Sophia credits be rejected when applying for a Master?

[Tswede]

My wife got her Associate's from TESU and her Bachelor's from Excelsior in the early 2000s. She used a lot of portfolio assessment, CLEP, NYU foreign language testing and Dantes testing.

She was admitted to all the masters programs she applied to and they never questioned her work. In fact, one of her advisors at the program she chose later said that they like students who do alternative methods as it shows a different kind of intelligence and drive to complete things independently, as long as other indicators speak to the student's ability to perform. She earned a 4.0 in her 60-hour master's program, so clearly they were right to admit her.

You can't get any guarantees that you will or won't get into any program, ever. If you don't get in to somewhere though, it's because your background doesn't fit what they look for in a student which could be for a million reasons. If you do get in somewhere it will be because they see you as a good fit for their program.